Four independent molecular prion protein parameters for discriminating new cases of C, L, and h bovine spongiform encephalopathy in cattle.

نویسندگان

  • Jan P M Langeveld
  • Jo H F Erkens
  • Ines Rammel
  • Jorg G Jacobs
  • Aart Davidse
  • Fred G van Zijderveld
  • Alex Bossers
  • Hermann Schildorfer
چکیده

In anticipation of the emergence of more variants of bovine spongiform encephalopathy (BSE), a semiquantitative display of the following four independent molecular diagnostic prion parameters was designed: N terminus, proteinase K (PK) resistance, glycoprofile, and mixed population. One H BSE case, three L BSE cases, six C BSE cases, and one unusual classical BSE (C BSE) case are reported.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 49 8  شماره 

صفحات  -

تاریخ انتشار 2011